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1. Multi-systemic disease with multiple symptom presentations
- Systemic: fatigue, malaise, chills, sweats, fever, weakness
- Cognitive: ¤memory and concentration, slow processing speed, disorientation
- Neurologic: paresthesias, tics and twitches, imbalance, shooting pains, headaches, vision, hearing
- Joints and muscles: Chest: GI: GU: Endocrine
2. Variable severity of the illness due to multi-factorial reasons
- Genetic predisposition
- Environmental toxicity's
- Other illnesses, allergies and injuries
- Nutritional, social, spiritual
3. Multiple organism causation often requiring multiple treatments
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